Monitoring the Cold Chain of RNA Vaccines

Our Ultra-low temperature data loggers are designed to monitor the transport and storage of RNA vaccines at extremely low temperatures, such as those encountered when using dry ice. Developed specifically for recording temperatures of products and vaccines well below freezing, these loggers maintain a high accuracy and failure-resistance even at very low temperatures. They are ideally suited for temperature monitoring of novel vaccines such as the RNA vaccines for COVID-19.

Our LogTag data loggers record temperatures in a measuring range from -80 °C (SRIL/TRIL) and -90 °C to +40 °C.

Data Logger for Frozen and Dry Ice Transports down to -80 °C

Transport Data Logger - LogTag® TRIL-8

Transport Data Logger - LogTag® TRIL-8

Record extremely low temperatures well below freezing point with our TRIL-8 temperature data logger. This logger can be configured multiple times for different recording intervals and alarm thresholds between -80 °C and +40 °C.

  • Multiple configuration possible
  • Measurement range -80 °C ~ +40 °C
  • Highly flexible alarm threshold configuration
  • For long-term monitoring of low temperatures
Topseller Single-Trip Transport Data Logger - LogTag SRIL-8

Single-Trip Transport Data Logger - LogTag SRIL-8

The SRIL-8 temperature logger is designed for one-time configuration, making it ideal as a cost-effective logger for monitoring transport and storage conditions well below-freezing temperatures.

  • One-time configuration
  • Measurement range -80 °C ~ +40 °C
  • Cost-effective solution
  • Ideal for constant thresholds
    Learn more about SRIL-8

Data Logger for Frozen and Dry Ice Transports down to -90 °C

LogTag TREL-8 mit externem Sensor

With Remote Probe - LogTag TREL-8 

Dhe TREL-8 data logger has been specially designed for use at ultra-low temperatures and is characterized by its external, food-safe probe. This allows for example the measurement of temperature data in a chest freezer without the need to remove the probe or to open the chest. Ideal for temperature monitoring during vaccine storage.

  • Food-rated probe
  • Up to 8.000 measured values in a measuring range from -90 °C to +40 °C
  • For deployments where the location to be measured is best reached with a remote probe
LogTag TREL30-16 mit externem Sensor

With Remote Probe and Display - LogTag TREL30-16

With the TREL30-16 data logger with 30-day statistics display and alarm, you have your ultra-low temperatures firmly under control. Designed specifically for use in ultra-low freezing temperatures, it is ideally suited for monitoring low-temperature storage facilities.

  • Food-rated probe
  • Up to 16,000 measured values in a measuring range from -90 °C to +40 °C
  • Alerting and display


LogTag UTREL-16 mit externem Sensor

With integrated USB, external Probe and Display - LogTag UTREL-16

The LogTag® UTREL-16F temperature data logger can record up to 16,000 readings in a measuring range from -90 °C to +40 °C via the external sensor. The UTREL-16F data logger is a cost-effective and reliable LOW-temperature USB data logger with display

  • Food-rated probe
  • Up to 16,000 measured values in a measuring range from -90 °C to +40 °C 
  • interated USB
  • Alerting and display
LogTag UTREL30-16 mit externem Sensor

With USB, external Probe and Display - LogTag UTREL30-16 DUAL

Temperature measurement where access requires a remote probe and data needs to be accessed without a PC. The LogTag UTREL30-16 DUAL provides the facility to create a detailed PDF report without need for extra accessories and proprietary software only with the supplied USB cable. The display is designed to show ‘at a glance’ if temperature excursions have occurred during the current day and up to the previous 30 days.

  • Food-rated probe
  • Up to 32,000 measured (16,000 per channel) values in a measuring range from -90 °C to +40 °C
  • Alerting and 30-Day-Statistics-Display
LogTag UTREL30-WiFi mit externem Sensor

With WiFi, USB, external Probe and Display - LogTag UTREL30-WiFi DUAL

The LogTag® UTREL30-WiFi DUAL is a 30 day ultra low temperature wifi logger with display, The LogTag® UTREL30-WiFi DUAL temperature data logger automatically uploads real-time temperature data to your LogTag® Online cloud account via your existing wireless network.
The large, easy-to-read display, is designed to show ‘at a glance’ if temperature excursions have occurred during the current day and up to the previous 30 days.

  • Food-rated probe
  • Up to 32,000 measured (16,000 per channel) values in a measuring range from -90 °C to +40 °C  via WiFi to the LogTag Online Cloud
  • Alerting and display

Vaccines are key components in disease prevention and control. It is of the utmost importance that vaccines are handled carefully, kept in the right conditions and at the right temperatures at all times. The quality of a vaccine is everyone's joint responsibility, from the manufacture to the administration of the vaccine.

The Vaccine Cold Chain 

The cold chain typically consists of several temperature-controlled environments where vaccines are kept and distributed in optimal conditions. It starts with the cold store in the production plant and extends via the transport of vaccines to the distributor. From there, the vaccines are delivered to the supply facility, where they are stored. The cold chain ends when the vaccine is administered to the patient. It is important to properly handle and store vaccines at every link in the cold chain.

Errors in storage and handling can result in high costs through wasted vaccines and unnecessary re-vaccinations. They can also lead to a patient's loss of confidence if repeated vaccinations are required.

Organizations such as the WHO, the FDA and the European Commission understand that quality must play a central role and have collaborated to define new and critical standards. They emphasize that measures must be taken to ensure consumer safety. Both companies and non-profit organizations understand the importance of change. Therefore, continuous safeguarding and monitoring the correct temperature of these products is the only way!

  • Vaccines must be properly stored from manufacture to administration.
  • Joint responsibility of manufacturers, distribution channels, medical personnel and health care providers.

    Storage of Vaccines

    Effective vaccine management has many variables including the type of refrigeration unit used, the way the product is loaded into the unit, how often and for how long doors are opened, and the ambient/outside temperature at the refrigerator's location. All have an influence on the temperature of the stored vaccine.

    Too much exposure to heat, cold or light at any step of the cold chain can damage vaccines, resulting in loss of vaccine efficacy. Any exposure to abnormal conditions further reduces the vaccine's potency. While inappropriate conditions can affect the effectiveness of cold-stored vaccines, one-time exposure to freezing temperatures will even destroy some. For example, liquid vaccines containing an adjuvant may lose their effectiveness when exposed to freezing temperatures. Novel RNA vaccines, on the other hand, require extremely low temperatures of up to -80 °C.

    Against this background, maintaining adequate and stable temperatures in vaccine refrigerators, freezers and controlled storage units is a critical and driving necessity. All this underlines the need for reliable temperature monitoring to ensure that temperature-sensitive medicines are kept within certain temperature ranges.

    Manual and Digital Temperature Documentation

    Temperature monitoring is an important part of good storage and handling practices. It is recommended to use calibrated, digital data loggers with an up-to-date and valid calibration certificate.

    Several types of temperature monitoring devices are available:
    Tip: Use only calibrated devices with a current calibration certificate. 

    Manual and Digital Temperature Documentation

    The amount of temperature documentation required for stored products has traditionally been a real burden for pharmacy managers, vaccine program coordinators/providers, hospitals, and labs. 

    Daily checks, manual documentation of minimum and maximum temperatures, and internal guidelines for temperature protocols can affect staff productivity and disrupt their primary focus - which should be patient care.

    Digital temperature data loggers are a cost-effective alternative to Min/Max thermometers. These offer several advantages over classic thermometers.

    Advantages of digital data loggers:
    • Digital temperature display is available outside the cooling environment
    • Remote probes can be used to record inside vessels such as vials
    • Alerting functions
    • Display of current and Min/Max temperatures
    • Large memory for measured data
    • Configurable recording intervals

    Automated Temperature Monitoring with Alarming Function

    Additionally to using individual data loggers, fully automated systems for temperature monitoring of vaccines are also available.

    These offer the advantage that temperature alarms can be sent by email or SMS. In this way, employees can be made aware of temperature fluctuations in time. Automatic temperature monitoring is particularly worthwhile with large vaccine stocks in order to be able to react to temperature fluctuations in a timely manner.

    Data Loggers with WHO-PQS Qualification

    The WHO mandates strict guidelines for the storage and monitoring of vaccines.

    Here you will find an overview of our WHO-pre-qualified data loggers- Simply use the "WHO PQS qualified" filter.